Cyclavance (cyclosporine oral solution) for Dogs
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Details
Atopic dermatitis is an itchy skin disease that may cause your dog to rub, lick, bite or scratch her skin. Cyclavance (cyclosporine oral solution) for Dogs is an oral form of cyclosporine indicated for the control of atopic dermatitis in canine companions weighting at least 4 pounds (18.8kg).
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Specifications
| Item Number | 321902 |
|---|---|
| Administration Form | Oral |
| Common Brand Name(s) | Atopica |
| For Use With | Dogs |
| Generic Name | Cyclosporine |
| Lifestage | Adult |
| Product Form | Liquid |
| Health Condition | Allergies |
| Drug Type | Immunosuppressant |
Uses
CYCLAVANCE is indicated for the control of atopic dermatitis in dogs weighing at least 4 lbs (1.8 kg) body weight.
Possible Side Effects
Side effects include vomiting, diarrhea, pruritus, depression, and lethargy
Drug & Food Interactions
CYCLAVANCE should be used with caution with drugs that affect the P-450 enzyme system. Simultaneous
administration of CYCLAVANCE with drugs that suppress the P-450 enzyme system, such as azoles (e.g. ketoconazole), may lead to increased plasma levels of cyclosporine. Killed vaccines are recommended for dogs receiving CYCLAVANCE because the impact of cyclosporine on the
immune response to modified live vaccines is unknown.
Precautions
Wear gloves during and wash hands after administration. Gastrointestinal problems and gingival hyperplasia may occur at the initial recommended dose of cyclavance oral solution for dogs. Cyclavance oral solution for dogs should be used with caution: 1. in cases with diabetes mellitus as it may cause elevated levels of serum glucose.2 in dogs with renal insufficiency since the effect of cyclosporine use on dogs with compromised renal function has not been studied Cyclvance is contraindicated for use in dogs with a history of neoplasia. Do not use in dogs with a hypersensitivity to cyclosporine. Cyclavance is a systemic immunosuppressant that may increase the susceptibility to infection and the development of neoplasia.
Ingredients
Ingredients
Cyclosporine oral solution
Instructions
Recommended Dosage
The initial dose of cyclavance is 5mg/kg/day as a single dose for 30 days. Following this initial daily treatment period , the dose of cyclavance may be tapered by decreasing the frequency of dosing to every other day or twice weekly, until a minimum frequency is reach which will maintain the desired therapeutic effect. Cyclavance should be given at least one hour before or two hours after a meal. If a dose is missed the next dose should be administered( without doubling) as soon as possible but dosing should be no more frequent than once daily. The dispensing system for the 15mL vial sizes includes a 1mL oral dosing syring graduated in 0.05 mL increments. To dose the dog, administer 0.05 mL of cyclavance per 2.2lbs of body weight. Do Not rinse or clean the oral dosing syringe between uses.
Storage Instructions
Room Temperature
FAQ
What is CYCLAVANCE?
CYCLAVANCE is an oral solution of cyclosporine that lowers the immune response. CYCLAVANCE selectively acts on the immune cells involved in the allergic reaction. CYCLAVANCE reduces the inflammation and itching associated with atopic dermatitis.
What kind of results can I expect when my dog takes CYCLAVANCE for the control of atopic dermatitis?
CYCLAVANCE should be given daily until improvement is seen. This will generally be the case within 30 days. You should contact your veterinarian if you are not satisfied with your dog’s response. Once the signs of atopic dermatitis are satisfactorily controlled, your veterinarian may reduce the frequency of administration of the product. Dose adjustment should only be carried out in consultation with your veterinarian. Your veterinarian will perform a clinical assessment at regular intervals and adjust the frequency of administration up or down according to the clinical response obtained.
What dogs should not take CYCLAVANCE?
Your dog should not be given CYCLAVANCE if s/he:
* Has a history of cancer or may possibly have cancer.
* Has a history of seizures, diabetes mellitus, and infections.
* Is hypersensitive to cyclosporine.
What to discuss with your veterinarian before giving CYCLAVANCE to your dog.
Tell your veterinarian about:
* Any digestive upset (vomiting or diarrhea) your dog has had
* Any history of lack of appetite and/or weight loss your dog has had
* Any serious disease or health conditions your dog has had
* Any allergies that your dog has now or has had
* Any medications (specifically any azoles (e.g. ketoconazole and/or steroids) that you are giving your dog or plan to give your dog, including those you can get without prescription (over the counter) and any dietary supplements
* If you plan to breed your dog, or if your dog is pregnant or nursing
Talk to your veterinarian about:
* What tests might be done before CYCLAVANCE is prescribed
* The potential side effects your dog may experience while taking CYCLAVANCE
* How often your dog may need to be examined by your veterinarian
* The risks and benefits of using CYCLAVANCE
| Strength | 100-mg/mL, 100-mg/mL |
|---|---|
| Size | 50mL, 15mL |
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